VENTILATOR-ASSOCIATED PNEUMONIA AND MORTALITY: THE ROLE OF THE SOFA SCORE

Authors

  • Renan Mateus de Oliveira Departamento de Enfermagem da Universidade Estadual de Ponta Grossa (UEPG ), Ponta Grossa, Paraná, Brasil.
  • Carla Luiza da Silva Departamento de Enfermagem da Universidade Estadual de Ponta Grossa (UEPG ), Ponta Grossa, Paraná, Brasil.
  • Simonei Bonatto Departamento de Enfermagem da Universidade Estadual de Ponta Grossa (UEPG ), Ponta Grossa, Paraná, Brasil.
  • Péricles Martim Reche Departamento de Enfermagem da Universidade Estadual de Ponta Grossa (UEPG ), Ponta Grossa, Paraná, Brasil.
  • Dyenily Alessi Sloboda Departamento de Enfermagem da UNICENTRO, Guarapuava, Paraná, Brasil .
  • Evellin Kauane de Oliveira Departamento de Enfermagem da Universidade Estadual de Ponta Grossa (UEPG ), Ponta Grossa, Paraná, Brasil.
  • Aiury Ribeiro de Souza Departamento de Enfermagem da Universidade Estadual de Ponta Grossa (UEPG ), Ponta Grossa, Paraná, Brasil.

DOI:

https://doi.org/10.26694/repis.v12i1.6855

Keywords:

Ventilator-Associated Pneumonia, Management indicators, Nursing, Intensive Care Unit, Organ Dysfunction Scores

Abstract

ABSTRACT: Objective: To assess the effectiveness of the SOFA score as a predictor of mortality in patients who developed ventilator-associated pneumonia (VAP) during ICU hospitalization. Method: Epidemiological, retrospective study conducted in a university hospital in Paraná, Brazil, including 39 ICU patients diagnosed with ventilator-associated pneumonia. The study was approved by the ethics committee (CAAE: 61430822.0.0000.0105). Results: The sample predominantly consisted of male patients (66.67%), with a mean age of 58.72 years. The mean initial SOFA score was 8.76, while the final SOFA score was 6.39. The analysis showed that patients who were discharged had a significantly lower initial SOFA score (p=0.01) and an even lower final SOFA score (p=0.001). Length of hospital stay had a moderate influence on the initial SOFA score (p=0.05), suggesting that prolonged hospitalization may impact VAP severity. Conclusion: The SOFA score proved to be an important predictor of clinical outcomes in VAP patients, assisting in ICU assessment and decision-making.

Descriptors: Pneumonia, Ventilator-Associated, Nursing, Health Status Indicators, ICU, Organ Dysfunction Scores.

References

1. Da Silva HS, Almeida Dos Santos A, Dos Santos Nunes N, Affonso Luna A. Nursing interventions related

to mechanical ventilation in serious patients affected by covid -19. Rev Elet. Ciên Tecn Inov Saúde. 2021 May

14;2:36–48.

2. Saganski GF, Padilha AP, Rowe MC, Falkoski A, Vasques JR. Cuidados de enfermagem no pós -operatório

imediato de cirurgia cardíaca em pacientes pediátricos: revisão de escopo. Rev Soc Bras Enferm Ped.

2022;22:eSOBEP2022014.

3. Centers for Disease Control and Prevention (CDC). Pneumonia Ventilator -associated and non-ventilatorassociated Pneumonia. Event. CDC. 2025;

4. Núñez SA, Roveda G, Zárate MS, Emmerich M, Verón MT. Ventilator -associated pneumonia in patients

on prolonged mechanical ventilation: Description, risk factors for mortality, and performance of the SOFA

score. Jorn Bras Pneum. 2021;47(3).

5. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, et al. The SOFA (Sepsis -related

Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med. 1996; 22(7):707 –

10.

6. Lopes Ferreira F, Peres Bota D, Bross A, Mélot C, Vincent JL. Serial evaluation of the SOFA score to

predict outcome in critically ill patients.JAMA. 2001 Oct 10;286(14):1754–8.

7. Instituto Latino-Americano de Sepse. Sepse: um problema de sa úde pública. Brasília: Conselho Federal de

Medicina; 2015. 89 p.

8. Indriasari, Aditya R, Al -Haq MM. Mortality risk factors and the ventilator-associated pneumonia (VAP) in

the ICU of a tertiary hospital in Indonesia. Anaesthesia, Pain and Intensive Care. 2024 Apr 1;28(2):206–13.

9. Cuschieri S. The STROBE guidelines. Saudi J Anaesth. 2019;13(5):S31–4.

10. Secretaria da Saúde Estado do Paraná (SESA). Regionais de Saúde. SESA:Curitiba [Internet]. 2024;1–3.

Available from: http://www.saude.pr.gov.br/modules/conteudo/conteudo.php?conteudo=2752

11. Hongwei Y, Juan W, Hui J, Zhongjian L, Xueying L, Rui L, Min L, Xiu W. Risk factors of ventilator -

associated pneumonia in patients with acute exacerbation of chronic obstructive pulmonary disease: a meta -

analysis and systematic review.BMC Pulm Med. 2025 ;25(1):558.

12. Luo W, Xing R, Wang C. The effect of ventilator -associated pneumonia on the prognosis of intensive care

unit patients within 90 days and 180 days. BMC Infect Dis. 2021 Dec 1;21(1).

13. Moretti M, Van Laethem J, Minini A, Pierard D, Malbrain MLNG. Ventilator-associated bacterial

pneumonia in coronavirus 2019 disease, a retrospective monocentric cohort study. Jour Infection and

Chemot. 2021 Jun 1;27(6):826–33.

14. Dehghani A, Abdeyazdan G, Davaridolatabadi E. An Overview of the Predictor Standard Tools for

Patient Weaning from Mechanical Ventilation. Electron Physician. 2016 Feb 25;8(2):1955-63.

15. Ochoa P, Mendoza AR, Molano D, Masclans JR, Parada -Gereda HM. Risk factors and outcomes of

ventilator-associated pneumonia: an updated systematic review and meta -analysis. BMC Pulm Med.

2025;25(1):453.

16. Chittawatanarat K, Jaipakdee W, Chotirosniramit N, Chandacham K, Jirapongcharoenlap T.

Microbiology, resistance patterns, and risk factors of mortality in ventilator -associated bacterial pneumonia

in a Northern Thai tertiary-care university based gener al surgical intensive care unit.Infect Drug Resist. 2014

Aug 16;7:203–10.

Published

2026-05-03

How to Cite

Oliveira, R. M. de, Silva, C. L. da, Bonatto, S., Reche, P. M., Sloboda, D. A., Oliveira, E. K. de, & Souza, A. R. de. (2026). VENTILATOR-ASSOCIATED PNEUMONIA AND MORTALITY: THE ROLE OF THE SOFA SCORE. Journal of Infection Prevention and Health, 12(1). https://doi.org/10.26694/repis.v12i1.6855

Similar Articles

1 2 3 4 5 6 > >> 

You may also start an advanced similarity search for this article.