Demographic and clinical characterization of hospital-acquired pneumonia cases not associated with mechanical ventilation

Abstract

Objective: To characterize the hospitalized adult who develop hospital-acquired pneumonia not associated with mechanical ventilation according to demographic, clinical, and therapeutic variations. Methods: Descriptive, cross-sectional, and quantitative research, carried out in a tertiary hospital in northern Paraná; cases notified by the Hospital Infection Control Commission were considered, through the healthcare-associated infections (HAIs) notification records of adults over or equal to 18 years old during 2020’s first trimester. Results: Regarding gender, there was similarity, with a higher prevalence in people over 60 years old and with length of stay deemed prolonged; about the clinical variables, it resulted in 50.6% of blood cultures associated with negative pneumonia, with 53.6% progressing to death. With respect to tracheal secretion cultures, a higher index of Acinetobacter baumanni, Staphylococcus spp, and Klebsiella pneumoniae was obtained, respectively, by using the Tazocin, Vancomycin, and Meropenem antimicrobials. Conclusion: The hospital-acquired pneumonia not associated with mechanical ventilation cases occurred proportionally between the genders, prevailing in the elderly and progressing to death in more than a half of the individuals. The clinical profile of tracheal secretions reveals Acinetobacter baumanni, Staphylococcus spp, and Klebsiella pneumoniae, with an antimicrobial’s therapeutic choice from the following classes: cephalosporins, carbapenems, glycopeptides, glycylcyclines, and polypeptides.